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Results for "

Echinomycin

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106101
    Echinomycin
    4 Publications Verification

    Quinomycin A; NSC-13502

    		 HIF/HIF Prolyl-Hydroxylase Antibiotic Bacterial Cancer
    Echinomycin (Quinomycin A) is potent small-molecule and cell-permeable inhibitor of hypoxia-inducible factor-1 (HIF-1) DNA-binding activity. Echinomycin selectively inhibits the cancer stem cells (CSCs) with an IC50 of 29.4 pM .
    Echinomycin
  • HY-161425
    Antitumor agent-149

    		Apoptosis Cancer
    Antitumor agent-149 (Compound 3) is an analogue of Echinomycin (HY-106101). Antitumor agent-149 inhibits HIF-1α-mediated transcription. Antitumor agent-149 induces cancer cell apoptosis. Antitumor agent-149 inhibits tumor growth in SW620 xenograft mice model .
    Antitumor agent-149

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