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Results for "

Eclipta alba

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0551
    Wedelolactone
    15+ Cited Publications

    Caspase Lipoxygenase Apoptosis Inflammation/Immunology Cancer
    Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibits the IKK Complex. Wedelolactone also inhibits 5-lipoxygenase (5-Lox) with an IC50 of 2.5 μM. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt. Wedelolactone can extract from Eclipta alba, and it can be used for the research of cancer .
    Wedelolactone
  • HY-N5100

    Others Cardiovascular Disease
    Isodemethylwedelolactone is a kind of procoagulant and haemolytic constituent isolated from Eclipta alba .
    Isodemethylwedelolactone
  • HY-N2191

    Others Inflammation/Immunology
    Ecliptasaponin D is a triterpenoid glucoside isolated from Eclipta alba (L.) Hassk which is the aerial part of Eclipta prostrate. Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant and immunomodulatory [1,2].
    Ecliptasaponin D
  • HY-N2028

    Ser/Thr Protease Cancer
    Demethylwedelolactone is a naturally occurring coumestan isolated from Eclipta alba. Demethylwedelolactone is a potent trypsin inhibitor with an IC50 of 3.0 μM. Demethylwedelolactone suppresses cell motility and cell invasion of breast cancer cell .
    Demethylwedelolactone
  • HY-N0551R

    Caspase Lipoxygenase Apoptosis Inflammation/Immunology Cancer
    Wedelolactone (Standard) is the analytical standard of Wedelolactone. This product is intended for research and analytical applications. Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibits the IKK Complex. Wedelolactone also inhibits 5-lipoxygenase (5-Lox) with an IC50 of 2.5 μM. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt. Wedelolactone can extract from Eclipta alba, and it can be used for the research of cancer .
    Wedelolactone (Standard)

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