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FR 173657

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15791
    FR173657

    FK-3657

    		 Bradykinin Receptor Inflammation/Immunology
    FR173657 is an orally active bradykinin B2 receptor antagonist (IC50: 0.56, 1.5, 2.9 nM for pig, rat, human B2 receptor respectively). FR173657 (p.o.) inhibits BK-induced bronchoconstriction in guinea-pigs (ED50: 0.075 mg/kg). FR173657 (p.o.) also inhibits Carrageenin-induced paw oedema in mice (ED50: 6.8 mg/kg). FR173657 can be used for research of inflammatory disease .
    FR173657

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