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GCGR antagonist2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148844
    GCGR antagonist 2

    		GCGR Metabolic Disease
    GCGR antagonist 2, a Furan-2-carbohydrazide, is an orally active glucagon receptor antagonist. GCGR antagonist 2 binds to hGluR with an Kd value of 2.3 nM, and inhibits rat receptor with an IC50 value of 0.43 nM. GCGR antagonist 2 inhibits glucagon-stimulated glycogenolysis .
    GCGR antagonist 2

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