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GSK1120212-<sup>13</sup>C,d<sub>3</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10999S2
    Trametinib-13C,d3

    GSK1120212-<sup>13sup>C,d<sub>3sub>; JTP-74057-<sup>13sup>C,d<sub>3sub>

    		 Isotope-Labeled Compounds MEK Autophagy Apoptosis Cancer
    Trametinib- 13C,d3 is the 13C- and deuterium labeled Trametinib. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis[1][2].
    Trametinib-13C,d3

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