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HAdV

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CMV (2) Dihydroorotate Dehydrogenase (2) DNA/RNA Synthesis (3) Isotope-Labeled Compounds (1) ROR (2) SARS-CoV (1)
By Research Areas:	Cancer (2) Infection (3)

4

Inhibitors & Agonists

2

Recombinant Proteins

2

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Braco-19 4 Publications Verification	CMV DNA/RNA Synthesis	Cancer
Braco-19 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor .

Braco-19 trihydrochloride 4 Publications Verification	DNA/RNA Synthesis CMV	Infection Cancer
Braco-19 trihydrochloride is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor .

RORγ/DHODH-IN-1	ROR Dihydroorotate Dehydrogenase DNA/RNA Synthesis Isotope-Labeled Compounds	Infection
RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC₅₀ values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5) .

RORγ/DHODH-IN-2	Dihydroorotate Dehydrogenase ROR SARS-CoV	Infection
RORγ/DHODH-IN-2 (Compound 1311) is an orally active dual inhibitor of RORγ/DHODH with IC₅₀ values of 11.9 nM and 90 nM, respectively. RORγ/DHODH-IN-2 exhibits antiviral activity by inhibiting the activity of SARS-CoV-2, HCMV, HAdV5, and MPXV, with IC₅₀ values of 27 nM, 20 nM, 9.1 nM, and 1.8 nM, respectively .

Species:	Virus (2)
Tag:	His (2)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

	HAdV-E fiber Protein (sf9, His) Human mastadenovirus E (HAdV-E) fiber Protein (His)	Virus	Sf9 insect cells
	Human mastadenoviruses (HAdVs) are non-enveloped, double-stranded DNA viruses. Human adenovirus type 4 (HAdV-E4) is the only type in species Human mastadenovirus E (HAdV-E) thus far isolated from humans. HAdV-E4 infection is associated with acute respiratory disease. HAdV-E fiber Protein (sf9, His) is the recombinant Virus-derived HAdV-E fiber protein, expressed by Sf9 insect cells , with C-His labeled tag.

	*Encapsidation protein IVa2 Protein, HAdV-B (sf9, His)* Human mastadenovirus B (HAdV-B) encapsidation protein IVa2 (His)	Virus	Sf9 insect cells
	Encapsidation protein IVa2 Protein, HAdV-B (sf9, His) is the recombinant Virus-derived Encapsidation protein IVa2 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Encapsidation protein IVa2 Protein, HAdV-B (sf9, His) is 446 a.a., with molecular weight of ~52.06 KDa.

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Cat. No.	Product Name	Chemical Structure

RORγ/DHODH-IN-1
RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC₅₀ values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5) .

RORγ/DHODH-IN-2
RORγ/DHODH-IN-2 (Compound 1311) is an orally active dual inhibitor of RORγ/DHODH with IC₅₀ values of 11.9 nM and 90 nM, respectively. RORγ/DHODH-IN-2 exhibits antiviral activity by inhibiting the activity of SARS-CoV-2, HCMV, HAdV5, and MPXV, with IC₅₀ values of 27 nM, 20 nM, 9.1 nM, and 1.8 nM, respectively .

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