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Results for "

NSC 613862

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106423
    Mivobulin

    CI-980 free base; NSC 613862; (S)-(-)-NSC 613862

    		 Microtubule/Tubulin Cancer
    Mivobulin (NSC 613862) is a tubulin inhibitor, binds to tubulin in the region that overlaps the colchicine site, and inhibits tubulin polymerization. Mivobulin (NSC 613862) promotes the formation of abnormal polymers and a GTPase activity in the tubulin dimer. Anti-cancer activity .
    Mivobulin
  • HY-106423A
    Mivobulin isethionate

    CI-980; NSC 613862 isethionate; (S)-(-)-NSC 613862 isethionate

    		 Antifolate Microtubule/Tubulin Cancer
    Mivobulin (isethionate) (CI-980) is an orally active, brain-penetrant and potent folate antagonist and a tubulin-binding mitotic inhibitor. Mivobulin (isethionate) accumulates rapidly in L1210 and CHO/K1 cells to levels many-fold higher than those in the extracellular medium and efflux is also quite rapid. Mivobulin (isethionate) is promising for research of cancers .
    Mivobulin isethionate

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