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Results for "

PFK-1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123981
    5MPN

    		Phosphatase Cancer
    5MPN is a first-in-class, potent, orally active and selective 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) inhibitor. 5MPN appears to be a competitive inhibitor of the F6P binding site (Ki=8.6 μM). 5MPN does not inhibit PFK-1 or PFKFB3. 5MPN targets the sugar metabolism of tumors and suppresses proliferation of multiple human cancer cell lines [1].
    5MPN
  • HY-P2819
    Phosphofructokinase 1

    PFK1

    		 Others Others
    Phosphofructokinase 1 (PFK1) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Phosphofructokinase 1
  • HY-149960
    Antiparasitic agent-17

    		Parasite Infection
    Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC50s of 0.96 μM and 1.67 μM, respectively [1].
    Antiparasitic agent-17
  • HY-149919
    Antimalarial agent 23

    		Parasite Infection
    Antimalarial agent 23 is an antimalarial benzimidazole with IC50s of 0.08 μM and 0.10 μM for PfNF54 and PfK1, respectively. Antimalarial agent 23 has potent β-hematin inhibition activity. Antimalarial agent 23 does not directly inhibit the conversion of heme to hemozoin [1].
    Antimalarial agent 23

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