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Pathways Recommended: PROTAC
Results for "

PROTAC MLKL Degrader 2

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169072
    PROTAC MLKL Degrader-2

    		PROTACs Mixed Lineage Kinase Cancer
    PROTAC MLKL Degrader-2 (compound MP-1) is a PROTAC targeting MLKL (Mixed Lineage Kinase). PROTAC MLKL Degrader-2 is composed of PROTAC target protein ligand PROTAC MLKL Degrader-2 (HY-169072) (red part), E3 ligase ligand Thalidomide (HY-14658) (blue part) and PROTAC Linker N-Methylpiperazine (HY-78871) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-N-methylpiperazine (HY-169074) [1] .
    PROTAC MLKL Degrader-2
  • HY-169073
    TC13172-NH-COOH

    		Ligands for Target Protein for PROTAC Others
    TC13172-NH-COOH is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). TC13172-NH-COOH can be used for synthesis PROTAC MLKL Degrader-2 (HY-169072) .
    TC13172-NH-COOH
  • HY-169074
    Thalidomide-N-methylpiperazine

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide-N-methylpiperazine is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-N-methylpiperazine can be used to synthesize PROTAC MLKL Degrader-2 (HY-169072) to exhibit antinecroptotic activity on human cell lines and effectively degrade MLKL in the HT-29 xenograft mouse model .
    Thalidomide-N-methylpiperazine

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