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Results for "

Protective groups

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (1) Adenosine Receptor (1) Amino Acid Derivatives (6) Biochemical Assay Reagents (1) Drug-Linker Conjugates for ADC (5) E3 Ligase Ligand-Linker Conjugates (1) Interleukin Related (1) Ligands for E3 Ligase (2) Microtubule/Tubulin (3) Reactive Oxygen Species (1) TNF Receptor (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (2) Inflammation/Immunology (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W004864

Fmoc-(S)-2-(4-pentenyl)Ala-OH	Amino Acid Derivatives	Others
Fmoc-(S)-2-(4-pentenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active secretin analogs .

HY-W008024

Fmoc-Dab(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release .

HY-W007056

Fmoc-N-me-Trp(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .

HY-15740

Mc-MMAD	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Cancer
Mc-MMAD is a protective group (maleimidocaproyl)-conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a agent-linker conjugate for ADC.

HY-15741

Mc-MMAE Maleimidocaproyl-monomethylauristatin E	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Cancer
Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC.

HY-78933

Fmoc-MMAE	Microtubule/Tubulin ADC Cytotoxin	Cancer
Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC .

HY-W008034

Fmoc-L-Trp(Boc)-OH	Amino Acid Derivatives	Cancer
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .

HY-W006886

Fmoc-(R)-2-(7-octenyl)Ala-OH	Amino Acid Derivatives	Others
Fmoc-(R)-2-(7-octenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize inhibitor peptides that combinatorially inactivate ErbB1, ErbB2, and ErbB3 .

HY-W006937

Boc-D-(4-fmoc)-aminophenylalanine Boc-p-amino-D-Phe(Fmoc)-OH; Boc-D-phe(4-NH-fmoc)-OH	Amino Acid Derivatives	Others
Boc-D-(4-fmoc)-aminophenylalanine (Boc-p-amino-D-Phe(Fmoc)-OH) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with gonadotropin-releasing hormone antagonist activity .

HY-148339

Fmoc-VAP-MMAE	Drug-Linker Conjugates for ADC	Others
Fmoc-VAP-MMAE is a agent-linker conjugates for ADC. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE (HY-15162), with a protective Fmoc group .

HY-15578

McMMAF 4 Publications Verification Maleimidocaproyl monomethylauristatin F	Drug-Linker Conjugates for ADC	Cancer
McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for antibody-drug conjugates (ADC). McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent .

HY-78574

N-Benzoylcytidine	Others	Others
N-Benzoylcytidine is a substrate for uracil-cytidine kinase 1 (UCK1) and UCK2. N-Benzoylcytidine can be used to synthesize 2-OH protective groups for solid-phase RNA synthesis, as well as synthetic oligonucleotides for UV induction and targeted gene silencing in zebrafish embryos .

HY-W784557

O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol	Biochemical Assay Reagents	Others
O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography .

HY-15578G

McMMAF Maleimidocaproyl monomethylauristatin F	Drug-Linker Conjugates for ADC	Cancer
McMMAF GMP is a GMP grade McMMAF (HY-15578). McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for antibody-drug conjugates (ADC). McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent .

HY-103174

MRS1334	Adenosine Receptor	Cardiovascular Disease
MRS1334 is a potent and selective human adenosine A₃ receptor antagonist with K_is of 2.69 nM, >100 nM, >100 nM for hA₃, rA₁, rA_2A, respectively. MRS1334 blocks the protective effect of Cl-IB-MECA leading to significant bradycardia and elevated ST segment . MRS1334 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W584527

VH032 analogue-1	Ligands for E3 Ligase	Cancer
VH032 analogue-1 is a VH032 (HY-120217) analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH032 analogue-1 will remove the protective group under acidic conditions and be directly used for PROTAC molecular synthesis. VH032 analogue-1 is a key intermediate in the synthesis of PROTACs based on VHL ligands.

HY-W584528

VH032 analogue-2	Ligands for E3 Ligase	Cancer
VH032 analogue-2 is a VH032 (HY-120217) analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH032 analogue-2 will remove the protective group under acidic conditions, and can be directly used for the synthesis of PROTAC molecules. VH032 analogue-2 is a key intermediate for the synthesis of PROTACs based on VHL ligands.

HY-W584535

VH032-C3-Boc	E3 Ligase Ligand-Linker Conjugates	Cancer
VH032-C3-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C3-Boc will remove the protective group under acidic conditions and be directly used for PROTAC molecular synthesis. VH032-C3-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands.

HY-124750

NecroX-7	TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species	Cardiovascular Disease Inflammation/Immunology
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .

Cat. No.	Product Name	Type

HY-15578G

McMMAF (GMP) Maleimidocaproyl monomethylauristatin F (GMP)	Fluorescent Dye
McMMAF GMP is a GMP grade McMMAF (HY-15578). McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for antibody-drug conjugates (ADC). McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent .

Cat. No.	Product Name	Type

HY-W008034

Fmoc-L-Trp(Boc)-OH	Drug Delivery
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .

HY-15578G

McMMAF (GMP) Maleimidocaproyl monomethylauristatin F (GMP)	Biochemical Assay Reagents
McMMAF GMP is a GMP grade McMMAF (HY-15578). McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for antibody-drug conjugates (ADC). McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent .

HY-77957

1-O-Methyl-2-deoxy-D-ribose	Biochemical Assay Reagents
1-O-Methyl-2-deoxy-D-ribose is a ribose derivative that can be more conveniently obtained through a one-step reaction by introducing a methoxy protective group at the anomeric carbon position under acidic conditions. This facilitates the acquisition of 2-deoxy-D-ribose. 1-O-Methyl-2-deoxy-D-ribose can be utilized in research on the synthesis of chemical materials .

Cat. No.	Product Name	Target	Research Area

HY-W004864

Fmoc-(S)-2-(4-pentenyl)Ala-OH	Amino Acid Derivatives	Others
Fmoc-(S)-2-(4-pentenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active secretin analogs .

HY-W008024

Fmoc-Dab(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release .

HY-W007056

Fmoc-N-me-Trp(Boc)-OH	Amino Acid Derivatives	Others
Fmoc-N-me-Trp(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptide antibiotics with antibacterial activity against Pseudomonas aeruginosa .

HY-W006886

Fmoc-(R)-2-(7-octenyl)Ala-OH	Amino Acid Derivatives	Others
Fmoc-(R)-2-(7-octenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize inhibitor peptides that combinatorially inactivate ErbB1, ErbB2, and ErbB3 .

HY-W006937

Boc-D-(4-fmoc)-aminophenylalanine Boc-p-amino-D-Phe(Fmoc)-OH; Boc-D-phe(4-NH-fmoc)-OH	Amino Acid Derivatives	Others
Boc-D-(4-fmoc)-aminophenylalanine (Boc-p-amino-D-Phe(Fmoc)-OH) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with gonadotropin-releasing hormone antagonist activity .

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