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Pathways Recommended:	Neuronal Signaling JAK/STAT Signaling

Results for "

ST2/IL-33 signaling

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (2)
By Research Areas:	Inflammation/Immunology (2)

2

Inhibitors & Agonists

1

Inhibitory Antibodies

Targets Recommended: STK33 RGS Protein Interleukin Related IRAK Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Astegolimab 1 Publications Verification MSTT 1041A; RG 6149	Interleukin Related	Inflammation/Immunology
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting *ST2, the IL-33* receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research .

ST2-IN-1	Interleukin Related	Inflammation/Immunology
ST2-IN-1 (compound 31) is a Stimulation-2 (ST2) inhibitor, with an IC₅₀ value of 7 μM in AlphaLISA assay, and 7.19 μM in HEK-Blue assay. ST2-IN-1 effectively attenuats the ST2/IL-33 signaling in human mast cells .

Cat. No.	Product Name	Target	Research Area

Astegolimab 1 Publications Verification MSTT 1041A; RG 6149	Interleukin Related	Inflammation/Immunology
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting *ST2, the IL-33* receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research .

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