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Selisistat

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15452
    Selisistat
    180+ Cited Publications

    EX-527

    		 Sirtuin Inflammation/Immunology Cancer
    Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease .
    Selisistat
  • HY-15452B
    (R)-Selisistat

    (R)-EX-527

    		 Sirtuin Cancer
    (R)-Selisistat ((R)-EX-527) is a R-enantiomer of Selisistat. Selisistat (EX-527) is a potent and selective SIRT1 inhibitor with IC50 of 98 nM.
    (R)-Selisistat
  • HY-15452A
    (S)-Selisistat
    1 Publications Verification

    (S)-EX-527

    		 Sirtuin Cancer
    (S)-Selisistat ((S)-EX-527) is a potent and selective SIRT1 inhibitor, with an IC50 of 98 nM.
    (S)-Selisistat

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