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Results for "

TEAD4

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125269
    TED-347
    5+ Cited Publications

    YAP Cancer
    TED-347 is a potent, irreversible, covalent and allosteric inhibitor at YAP-TEAD protein-protein interaction with an EC50 of 5.9 μM for TEAD4⋅Yap1 protein-protein interaction. TED-347 specifically and covalently bonds with Cys-367 within the central pocket of TEAD4 with a Ki of 10.3 μM. TED-347 blocks TEAD transcriptional activity and has antitumor activity .
    TED-347
  • HY-139330

    Apoptosis Cancer
    MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion .
    MGH-CP1
  • HY-RS14345

    Small Interfering RNA (siRNA) Others

    TEAD4 Human Pre-designed siRNA Set A contains three designed siRNAs for TEAD4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TEAD4 Human Pre-designed siRNA Set A
    TEAD4 Human Pre-designed siRNA Set A
  • HY-160657

    Others Others
    DC-TEADin04 has weak inhibitory activity against TEAD4 palmitoylation .
    DC-TEADin04

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