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Tryptophan (standard)

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

13

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0623R
    L-Tryptophan (standard)
    4 Publications Verification

    Tryptophan (standard); Tryptophane (standard)

    		 Others Metabolic Disease
    L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .
    L-Tryptophan (standard)
  • HY-100806R
    Kynurenic acid (Standard)
    3 Publications Verification

    Quinurenic acid (standard)

    		 iGluR Endogenous Metabolite Apoptosis CXCR GPR35 Neurological Disease Inflammation/Immunology Endocrinology
    Kynurenic acid (Standard) is the analytical standard of Kynurenic acid. This product is intended for research and analytical applications. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8.
    Kynurenic acid (Standard)
  • HY-W011978R
    N-Acetyl-L-tryptophan (Standard)

    		Endogenous Metabolite Metabolic Disease
    N-Acetyl-L-tryptophan (Standard) is the analytical standard of N-Acetyl-L-tryptophan. This product is intended for research and analytical applications. N-Acetyl-L-tryptophan is an endogenous metabolite.
    N-Acetyl-L-tryptophan (Standard)
  • HY-113227R
    Oxoadipic acid (Standard)

    		Endogenous Metabolite Metabolic Disease
    Oxoadipic acid (Standard) is the analytical standard of Oxoadipic acid. This product is intended for research and analytical applications. Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.
    Oxoadipic acid (Standard)
  • HY-W001171R
    3-Hydroxyanthranilic acid (Standard)

    		Endogenous Metabolite Others
    3-Hydroxyanthranilic acid (Standard) is the analytical standard of 3-Hydroxyanthranilic acid. This product is intended for research and analytical applications. 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.
    3-Hydroxyanthranilic acid (Standard)
  • HY-13055BR
    Telotristat (Standard)

    		Tryptophan Hydroxylase Neurological Disease Cancer
    Telotristat (Standard) is the analytical standard of Telotristat. This product is intended for research and analytical applications. Telotristat (LP-778902) is a potent tryptophan hydroxylase inhibitor with an in vivo IC50 of 0.028 μM.
    Telotristat (Standard)
  • HY-104026R
    L-Kynurenine (Standard)

    		Aryl Hydrocarbon Receptor Endogenous Metabolite Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
    L-Kynurenine (Standard)
  • HY-W012479R
    H-D-Trp-OH (Standard)

    		Endogenous Metabolite Metabolic Disease
    H-D-Trp-OH (Standard) is the analytical standard of H-D-Trp-OH. This product is intended for research and analytical applications. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.
    H-D-Trp-OH (Standard)
  • HY-77839R
    Cortodoxone (Standard)

    		Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Cortodoxone (Standard) is the analytical standard of Cortodoxone. This product is intended for research and analytical applications. Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .
    Cortodoxone (Standard)
  • HY-40161R
    Indole-3-carboxylic acid (Standard)

    		Endogenous Metabolite Metabolic Disease
    Indole-3-carboxylic acid (Standard) is the analytical standard of Indole-3-carboxylic acid. This product is intended for research and analytical applications. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases .
    Indole-3-carboxylic acid (Standard)
  • HY-100807R
    Quinolinic acid (Standard)
    3 Publications Verification

    		 Endogenous Metabolite iGluR Neurological Disease Inflammation/Immunology
    Quinolinic acid (Standard) is the analytical standard of Quinolinic acid. This product is intended for research and analytical applications. Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction .
    Quinolinic acid (Standard)
  • HY-113294R
    3-Hydroxykynurenine (Standard)

    3-Hydroxy-DL-kynurenine (standard)

    		 Endogenous Metabolite Apoptosis Neurological Disease
    3-Hydroxykynurenine (Standard) is the analytical standard of 3-Hydroxykynurenine. This product is intended for research and analytical applications. 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis .
    3-Hydroxykynurenine (Standard)
  • HY-W011417R
    Cinnabarinic acid (Standard)

    		Endogenous Metabolite mGluR Apoptosis Others
    Cinnabarinic acid (Standard) is the analytical standard of Cinnabarinic acid. This product is intended for research and analytical applications. Cinnabarinic acid is a specific orthosteric agonist of mGlu4 by interacting with residues of the glutamate binding pocket of mGlu4, has no activity at other mGlu receptors. Cinnabarinic acid is an endogenous metabolite of the kynurenine pathway of tryptophan. Cinnabarinic acid induces cell apoptosis .
    Cinnabarinic acid (Standard)
  • HY-W014502R
    D-Kynurenine (Standard)

    		Aryl Hydrocarbon Receptor Endogenous Metabolite Cancer
    D-Kynurenine (Standard) is the analytical standard of D-Kynurenine. This product is intended for research and analytical applications. D-kynurenine, a metabolite of D-tryptophan, can serve as the bioprecursor of kynurenic acid (KYNA) and 3-hydroxykynurenine. D-Kynurenine is an agonist for G protein-coupled receptor, GPR109B. D-Kynurenine is a substrate in a fluorometric assay of D-amino acid oxidase. D-kynurenine promotes epithelial-to-mesenchymal transition via activating aryl hydrocarbon receptor (AHR) .
    D-Kynurenine (Standard)
  • HY-W008820R
    Glutaric acid (Standard)

    		Endogenous Metabolite Metabolic Disease
    Glutaric acid (Standard) is the analytical standard of Glutaric acid. This product is intended for research and analytical applications. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I . In Vitro: Glutaric acid (GA) at concentrations of 1 and 2 mM is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM .
    Glutaric acid (Standard)

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