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Pathways Recommended: GPCR/G Protein MAPK/ERK Pathway
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Tshr/Gαq/PKC pathway

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107916
    Thyrotropin
    1 Publications Verification

    TSH; Pretiron

    		 Others Metabolic Disease Endocrinology
    Thyrotropin is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .
    Thyrotropin

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