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Results for "

UBE2N

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153775

    E1/E2/E3 Enzyme Cancer
    UC-764864 is a UBE2N inhibitor. UC-764864 inhibits UBE2N enzymatic activity. UC-764864 has cytotoxic effects and inhibition of UBE2N-dependent signaling in leukemic cells. UC-764864 blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines .
    UC-764864
  • HY-13811
    NSC697923
    1 Publications Verification

    E1/E2/E3 Enzyme Apoptosis Cancer
    NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity [2].
    NSC697923
  • HY-RS15356

    Small Interfering RNA (siRNA) Others

    UBE2N Human Pre-designed siRNA Set A contains three designed siRNAs for UBE2N gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    UBE2N Human Pre-designed siRNA Set A
    UBE2N Human Pre-designed siRNA Set A

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