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Results for "

Ubc13

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120934
    C25-140
    10+ Cited Publications

    		 TNF Receptor E1/E2/E3 Enzyme Inflammation/Immunology
    C25-140, a first-in-class, orally active, and fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity .
    C25-140
  • HY-13811
    NSC697923
    1 Publications Verification

    		 E1/E2/E3 Enzyme Apoptosis Cancer
    NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity .
    NSC697923
  • HY-157728
    ML307

    		E1/E2/E3 Enzyme Inflammation/Immunology
    ML307 is a potent, sub-micromolar, first-in-class Ubc13 enzyme activity inhibitor with an IC50 of 781 nM. ML307 has the potential for immunomodulation and inflammation research .
    ML307
  • HY-125660
    Leucettamol A

    		Others Infection
    Leucettamol A is an inhibitor of Ubc13-Uev1A interaction, with an IC50 of 50 μg/mL. Leucettamol A can be isolated from a marine sponge, Leucetta aff. Microrhaphis .
    Leucettamol A

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