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Ultraviolet Filter

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Androgen Receptor (2) Apoptosis (2) Biochemical Assay Reagents (4) Cytochrome P450 (4) ERK (2) Estrogen Receptor/ERR (4) Isotope-Labeled Compounds (2) PI3K (2) PPAR (3) Thyroid Hormone Receptor (2)
By Research Areas:	Cancer (1) Endocrinology (2) Metabolic Disease (6)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17587

4-Methylbenzylidene camphor 1 Publications Verification 4-MBC; Enzacamene	Apoptosis PI3K Akt ERK	Metabolic Disease
4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .

HY-109655

Ethylhexyl triazone Octyl triazone	Biochemical Assay Reagents	Others
Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.

HY-W099730

Bemotrizinol Tinosorb S	Others	Others
Bemotrizinol (Tinosorb S), an ultraviolet (UV) filter, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation .

HY-N3985

Gyrophoric acid	Others	Cancer
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC₅₀ value of 105.75 μg/ml .

HY-17587R

4-Methylbenzylidene camphor (Standard)	Apoptosis PI3K Akt ERK	Metabolic Disease
4-Methylbenzylidene camphor (Standard) is the analytical standard of 4-Methylbenzylidene camphor. This product is intended for research and analytical applications. 4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .

HY-107333

Cinoxate	PPAR	Metabolic Disease
Cinoxate is a hypertrophic peroxisome proliferator activating receptor γ (PPARγ) agonist with K_i value of 18.0 μM. Cinoxate can be used to study obesity .

HY-W749966

Octocrylene-d10	Isotope-Labeled Compounds	Metabolic Disease
Octocrylene-d10 is the deuterium labeled Octocrylene. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths .

HY-109655R

Ethylhexyl triazone (Standard)	Biochemical Assay Reagents	Others
Ethylhexyl triazone (Standard) is the analytical standard of Ethylhexyl triazone. This product is intended for research and analytical applications. Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.

HY-W099730R

Bemotrizinol (Standard) Tinosorb S (Standard)	Others	Others
Bemotrizinol (Standard) is the analytical standard of Bemotrizinol. This product is intended for research and analytical applications. Bemotrizinol (Tinosorb S), an ultraviolet (UV) filter, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation .

HY-W419643

Drometrizole trisiloxane	Others	Others
Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .

HY-A0087R

Octocrylene (Standard)	Biochemical Assay Reagents PPAR Estrogen Receptor/ERR Cytochrome P450	Others
Octocrylene (Standard) is the analytical standard of Octocrylene. This product is intended for research and analytical applications. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation .

HY-A0087

Octocrylene 2 Publications Verification	Biochemical Assay Reagents PPAR Estrogen Receptor/ERR Cytochrome P450	Others
Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .

HY-B1234

Octinoxate Octyl methoxycinnamate	Androgen Receptor Estrogen Receptor/ERR Thyroid Hormone Receptor Cytochrome P450	Metabolic Disease Endocrinology
Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

HY-B1234S

Octinoxate-13C,d3	Cytochrome P450 Thyroid Hormone Receptor Androgen Receptor Estrogen Receptor/ERR Isotope-Labeled Compounds	Metabolic Disease Endocrinology
Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3985

Gyrophoric acid	Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields Cancer	Others
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC₅₀ value of 105.75 μg/ml .

HY-B1234

Octinoxate Octyl methoxycinnamate	Structural Classification Natural Products other families Classification of Application Fields Source classification Other Diseases Cosmetic Research Plants Disease Research Fields	Androgen Receptor Estrogen Receptor/ERR Thyroid Hormone Receptor Cytochrome P450
Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

Cat. No.	Product Name	Chemical Structure

HY-W749966

Octocrylene-d10
Octocrylene-d10 is the deuterium labeled Octocrylene. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths .

HY-B1234S

Octinoxate-13C,d3
Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

Octinoxate-13C,d3

Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .

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