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Bemotrizinol  (Synonyms: Tinosorb S)

Cat. No.: HY-W099730 Purity: ≥98.0%
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Bemotrizinol (Tinosorb S), a compound that can absorb ultraviolet light, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation.

For research use only. We do not sell to patients.

Bemotrizinol Chemical Structure

Bemotrizinol Chemical Structure

CAS No. : 187393-00-6

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Based on 1 publication(s) in Google Scholar

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Description

Bemotrizinol (Tinosorb S), a compound that can absorb ultraviolet light, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation[1][2][3][4].

In Vitro

Bemotrizinol 可作为紫外线过滤剂,用于过滤 280-380 nm 范围内的紫外线辐射。Bemotrizinol 可用于防晒化妆品的研究,不引起皮肤渗透。含有 Bemotrizinol 负载纳米结构脂质载体 (NLC) 的载体的防晒系数值增加了约 20%[5]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Bemotrizinol can be used as a UV filter to filter UV radiation in the range of 280-380 nm. Bemotrizinol can be used in the study of sunscreen cosmetics without causing skin penetration. The SPF value of the carrier containing Bemotrizinol loaded nanostructured lipid carrier (NLC) increased by about 20%[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

627.81

Formula

C38H49N3O5

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CCCCC(CC)COC1=CC(=C(C=C1)C2=NC(=NC(=N2)C3=CC=C(C=C3)OC)C4=C(C=C(C=C4)OCC(CC)CCCC)O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Chloroform : 50 mg/mL (79.64 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5928 mL 7.9642 mL 15.9284 mL
5 mM 0.3186 mL 1.5928 mL 3.1857 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Chloroform 1 mM 1.5928 mL 7.9642 mL 15.9284 mL 39.8210 mL
5 mM 0.3186 mL 1.5928 mL 3.1857 mL 7.9642 mL
10 mM 0.1593 mL 0.7964 mL 1.5928 mL 3.9821 mL
15 mM 0.1062 mL 0.5309 mL 1.0619 mL 2.6547 mL
20 mM 0.0796 mL 0.3982 mL 0.7964 mL 1.9910 mL
25 mM 0.0637 mL 0.3186 mL 0.6371 mL 1.5928 mL
30 mM 0.0531 mL 0.2655 mL 0.5309 mL 1.3274 mL
40 mM 0.0398 mL 0.1991 mL 0.3982 mL 0.9955 mL
50 mM 0.0319 mL 0.1593 mL 0.3186 mL 0.7964 mL
60 mM 0.0265 mL 0.1327 mL 0.2655 mL 0.6637 mL
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Bemotrizinol Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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