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Results for "

anti-Plasmodium

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Cytochrome P450 (1) Dihydroorotate Dehydrogenase (1) FKBP (1) HSP (1) Parasite (5) Phosphodiesterase (PDE) (1)
By Research Areas:	Infection (6)

Inhibitors & Agonists

Screening Libraries

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119046

SNX-0723	HSP Parasite	Infection
SNX-0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX-0723 shows high binding affinity for HsHsp90 and PfHsp90 with K_is of 4.4 and 47 nM, respectively. SNX-0723 inhibits liver-stage P. berghei ANKA parasites with the EC₅₀ of 3.3 μM .

HY-149782

Phosphodiesterase-IN-1	Phosphodiesterase (PDE) Parasite	Infection
Phosphodiesterase-IN-1 (Compound 7) is a phosphodiesterase (PDE) inhibitor with anti-Plasmodium activity. Phosphodiesterase-IN-1 has antiproliferative activity against P. falciparum (strain 3D7) with an IC₅₀ value of 0.64 μM .

HY-13834

GW844520	Parasite Cytochrome P450	Infection
GW844520 is an orally active inhibitor of cytochrome bc1 complex. GW844520 can be used in malaria and anti-plasmodium related research .

HY-B1401

Euquinine Quinine ethyl carbonate	Others	Infection
Euquinine is an odorless salt that can be used as a substitute for quinine. Euquinine has anti-Plasmodium falciparum activity. Euquinine can be used for the study of multidrug resistance and bioavailability of Plasmodium falciparum .

HY-114215

DSM-421	Dihydroorotate Dehydrogenase Parasite	Infection
DSM-421 is an orally active Dihydroorotate dehydrogenase inhibitor. DSM-421 has antiplasmodium activity .

HY-W046346

D44	FKBP Parasite	Infection
D44 is a Plasmodium FKBP₃₅ inhibitor that selectively inhibits the FKBD35 PPIase activity, with PPIase IC₅₀ values of 132 nM and 125 nM for Plasmodium falciparum and Plasmodium vivax, respectively. D44 exhibits antiplasmodium activity and can be used in research related to infectious diseases .

Cat. No.	Product Name

HY-L082

Antiparasitic Compound library	489 compounds
A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs. MCE has a unique collection of 489 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.

Antiparasitic Compound library

489 compounds

A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs.

MCE has a unique collection of 489 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.

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