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cGAS-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149526
    cGAS-IN-1

    		Cyclic GMP-AMP Synthase Inflammation/Immunology
    cGAS-IN-1 (compound C20) is a flavonoid and Cyclic GMP-AMP Synthase (cGAS) inhibitor with IC50s of 2.28 μM (human cGAS) and 1.44 μM (mouse cGAS). Abnormal activation of cGAS is associated with a variety of immune-mediated inflammatory diseases, and cGAS-IN-1 has potential anti-inflammatory activity [1].
    cGAS-IN-1

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