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clinical RSV isolates

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122587
    AVG-233

    		DNA/RNA Synthesis RSV Infection
    AVG-233 is a potent, orally active RNA dependent RNA polymerase (RdRp) inhibitor. AVG-233 prevents initiation of the viral polymerase complex at the promoter. AVG-233 binding site is present in the L1-1749 fragment. AVG-233 has nanomolar activity against both RSV strains and clinical RSV isolates (EC50=0.14-0.31 μM). AVG-233 can be used for research of respiratory syncytial virus (RSV) .
    AVG-233
  • HY-123475A
    Sisunatovir hydrochloride
    2 Publications Verification

    RV521 hydrochloride

    		 RSV Infection
    Sisunatovir (RV521) hydrochloride, an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC50s of 1.4 nM and 1.0 nM, respectively .
    Sisunatovir hydrochloride
  • HY-123475
    Sisunatovir
    2 Publications Verification

    RV521

    		 RSV Infection
    Sisunatovir (RV521), an orally available inhibitor of the RSV protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC50s of 1.4 nM and 1.0 nM, respectively .
    Sisunatovir
  • HY-12993
    RSV604
    2 Publications Verification

    A-60444

    		 RSV Infection
    RSV604 (A-60444) is an inhibitor of respiratory syncytial virus (RSV) replication. RSV604 targets the nucleocapsid protein, with a Kd of 1.6 μM. RSV604 displays submicromolar activity against numerous clinical isolates of both the A and B subtypes of RSV (average EC50s=0.8 μM) .
    RSV604

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