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heart defects

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W099479
    Insect repellent M 3535

    Ethyl butylacetylaminopropionate; IR-3535

    		 Reactive Oxygen Species Apoptosis Cardiovascular Disease Inflammation/Immunology
    Insect repellent M 3535 (Ethyl butylacetylaminopropionate; IR-3535) is a novel potent anthelmintic that is toxic to zebrafish with a lethal concentration 50 (LC50) of 140 mg/L at 72 hours post fertilization (hpf). Insect repellent M 3535 causes morphological abnormalities and cardiac defects in early embryonic development of zebrafish by potentially inducing the production and accumulation of reactive oxygen species (Reactive Oxygen Species) and activating oxidative stress responses, thereby activating the endogenous apoptosis pathway .
    Insect repellent M 3535

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