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Results for "

phosphoinositide hydrolysis

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100841
    (Rac)-3-Hydroxyphenylglycine

    3HPG

    		 Others Metabolic Disease
    (Rac)-3-Hydroxyphenylglycine is an phosphoinositide hydrolysis agonist . ACPD: I-aminocyclopcntane-1,3-dicarboxylic acid.
    (Rac)-3-Hydroxyphenylglycine
  • HY-13410
    Xanomeline oxalate
    1 Publications Verification

    LY246708 oxalate

    		 mAChR Neurological Disease
    Xanomeline oxalate (LY246708 oxalate) is a potent and selective muscarinic receptor agonist (SMRA) and stimulates phosphoinositide hydrolysis in vivo. Xanomeline oxalate can be used for the research of Alzheimer’s disease .
    Xanomeline oxalate
  • HY-103566
    LY456236

    		mGluR EGFR Neurological Disease
    LY456236 is a selective, non-competitive and orally active mGlu1 receptor antagonist that inhibits phosphoinositide hydrolysis with an IC50 of 0.145 μM. LY456236 also inhibits EGFR with an IC50 of 0.91 μM .
    LY456236
  • HY-135464
    (±)-LY367385

    		mGluR Neurological Disease
    (±)-LY367385 is the racemate of LY367385. LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with > 100 μM for mGlu5a .
    (±)-LY367385
  • HY-101324A
    MK-212 monohydrochloride

    CPP monohydrochloride

    		 5-HT Receptor Neurological Disease
    MK-212 (CPP) monohydrochloride is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 monohydrochloride can stimulate phosphoinositide hydrolysis in cerebral cortex .
    MK-212 monohydrochloride
  • HY-107515
    LY367385
    2 Publications Verification

    		 mGluR Neurological Disease
    LY367385 is a highly selective and potent mGluR1a antagonist. LY367385 has an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 has neuroprotective, anticonvulsant and antiepileptic effects .
    LY367385
  • HY-145463
    α-Methylserotonin

    		5-HT Receptor Cardiovascular Disease
    α-Methylserotonin is a potent and selective agonist of 5-HT2 receptor.α-Methylserotonin is an analogue of serotonin formed in vivo from α-methyltryptophan.α-Methylserotonin mediates the lymphatic smooth muscle contraction and prevents the up-regulation of serotonin-receptor-mediated phosphoinositide hydrolysis .
    α-Methylserotonin
  • HY-125304
    L 363851

    		Neurokinin Receptor Endocrinology
    L 363851 is a Neurokinin 2 receptor agonist, and induces the contractile response of tracheal smooth muscle devoid of epithelium (IC50 of 3.2 nM) and phosphoinositide hydrolysis (IC50 of 36 μM).
    L 363851
  • HY-101630A
    Deramciclane fumarate

    EGIS-3886 fumarate

    		 5-HT Receptor Others
    Deramciclane fumarate is an antagonist of 5-HT Receptor. Deramciclane fumarate is an inverse agonist of 5-HT2C Receptor with an IC50 of 168 nM. Deramciclane fumarate also decreases basal phosphoinositide hydrolysis .
    Deramciclane fumarate
  • HY-101324
    MK-212

    CPP

    		 5-HT Receptor Neurological Disease
    MK-212 (CPP) is a centrally acting 5-HT1C/5-HT2 agonist. MK-212 can stimulate phosphoinositide hydrolysis in cerebral cortex .
    MK-212
  • HY-107515A
    LY367385 hydrochloride
    2 Publications Verification

    		 mGluR Neurological Disease
    LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects .
    LY367385 hydrochloride
  • HY-14609
    MPEP Hydrochloride
    3 Publications Verification

    		 mGluR Neurological Disease
    MPEP Hydrochloride is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP Hydrochloride has anxiolytic-or antidepressant-like effects . MPEP (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    MPEP Hydrochloride
  • HY-14609A
    MPEP
    3 Publications Verification

    		 mGluR Neurological Disease
    MPEP is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP has anxiolytic-or antidepressant-like effects . MPEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    MPEP

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