1. Epigenetics
  2. Histone Methyltransferase
  3. TDI-6118

TDI-6118 (Compound 5) is a potent inhibitor of EZH2. EZH2-IN-12 has the potential for the research of central nervous system malignancies.

For research use only. We do not sell to patients.

TDI-6118 Chemical Structure

TDI-6118 Chemical Structure

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Description

TDI-6118 (Compound 5) is a potent inhibitor of EZH2. EZH2-IN-12 has the potential for the research of central nervous system malignancies[1].

IC50 & Target

EZH2

 

Molecular Weight

460.35

Formula

C23H23Cl2N3O3

SMILES

CC1=CC(C)=C(C(N1C)=O)CN2CCC3=C(C=C(C(Cl)=C3C2=O)C4=C(ON=C4C)C)Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TDI-6118
Cat. No.:
HY-144330
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