2. Signaling Pathways
  3. Epigenetics
  4. Histone Methyltransferase
  5. NSD2/MMSET/WHSC1 Isoform

NSD2/MMSET/WHSC1

 

NSD2/MMSET/WHSC1 Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-161574
    LLC0424
    		Inhibitor 98.42%
    LLC0424 is a potent and selective cereblon-based PROTAC nuclear receptor-binding SET domain-containing 2 (NSD2) degrader. LLC0424 effectively degraded NSD2 with a DC50 of 20 nM in RPMI-8402 cells. LLC0424 selectively induces NSD2 degradation in a cereblon- and proteasome-dependent fashion. (Blue: CRBN ligand (HY-14658), Black: linker (HY-40002); Pink: NSD2 inhibitor (HY-161575)).