Piezo2 - piezo-type mechanosensitive ion channel component 2 Gene

Mus musculus

Also known as Fam38b; Fam38b2; 5930434P17; 9030411M15Rik; 9430028L06Rik

Gene ID: 667742 | Gene type: protein coding

About Piezo2

Summary

Enables mechanosensitive cation channel activity. Involved in detection of mechanical stimulus involved in sensory perception. Acts upstream of or within cation transport and regulation of membrane potential. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in dorsal root ganglion and lung. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2). [provided by Alliance of Genome Resources, Apr 2022]

Piezo2 Products(1)

mRNA	Protein	Name
NM_001039485.4	NP_001034574.4	piezo-type mechanosensitive ion channel component 2

Protein Preferred Names

Protein Names

piezo-type mechanosensitive ion channel component 2

family with sequence similarity 38, member B

family with sequence similarity 38, member B2

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P1410C	D-GsMTx4 TFA	Inhibitor	99.89%	Unkown
HY-131018	Jedi2		99.84%	Unkown
HY-P1410B	D-GsMTx4	Inhibitor	99.44%	Unkown
HY-RS16250	Piezo2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS10484	PIEZO2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Piezo2	NCBI	NCBI:63895

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