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Odulimomab  (Synonyms: anti-LFA1)

Cat. No.: HY-P99765

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Odulimomab (anti-LFA1) is an anti-LFA-1 monoclonal antibody. Odulimomab inhibits proliferation of T lymphocyte and shows protective effects against ischemia and reperfusion injury. Odulimomab can be used for the research of transplant rejection and immunological disease.

For research use only. We do not sell to patients.

CAS No. : 159445-64-4

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Odulimomab Related Antibodies

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Description

Odulimomab (anti-LFA1) is an anti-LFA-1 monoclonal antibody. Odulimomab inhibits proliferation of T lymphocyte and shows protective effects against ischemia and reperfusion injury. Odulimomab can be used for the research of transplant rejection and immunological disease[1][2].

Isotype

F(ab')2-G1-nd
Species

Mouse
In Vitro

Odulimomab inhibits proliferation of T lymphocyte, and cytotoxicity and antibody production of T and Natural Killer (NK) cells in vitro[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Odulimomab Related Antibodies
In Vivo

Odulimomab (1.5 and 0.75 mg/kg; i.p., 1.5 mg/kg for the first treatment then followed by daily injection of 0.75 mg/kg until sacrifice) shows protective effects against ischemia and reperfusion injury, and also repairs in renal function after transplantation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Cynomolgus Monkeys with renal damage ischemia and kidney autotransplantation[1]
Dosage: 1.5 and 0.75 mg/kg
Administration: Intraperitoneal injection; 1.5 mg/kg for the first dose and after pedicle clamping followed by daily injection of 0.75 mg/kg until sacrifice
Result: Decreased the creatinine level after ischemia and autotransplantation for 3 days and increased the potassium fraction reabsorption.
CAS No.
SMILES

[Odulimomab]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • F(ab')2-G1-nd
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Odulimomab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Odulimomab159445-64-4anti-LFA1IntegrinT lymphocyteNKischemia and reperfusion injuryrenalmonkeyInhibitorinhibitorinhibit

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