2. Signaling Pathways
  3. Cytoskeleton
  4. Integrin
  5. α1β1 Isoform

α1β1

 
Cat. No. Product Name Effect Purity
  • HY-107588
    TC-I 15
    		Inhibitor 99.80%
    TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin α2β1 inhibitor, and it also inhibits α1β1 and α11β1. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, .
Cat. No. Product Name / Synonyms Species Source