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  3. Enzymes & Regulators
  4. PADI4 Protein, Human (sf9, His)

PADI4 Protein, Human (sf9, His)

Cat. No.: HY-P77121
Handling Instructions

PADI4 is a hydrolase that converts arginine residues in histones to citrulline. PADI4 promotes tumor progression by up-regulating the cytokine receptor CXCR2. PADI4 can also cause inflammation and immune responses. PADI4 Protein, Human (sf9, His) is the recombinant human-derived PADI4 protein, expressed by Sf9 insect cells , with N-His labeled tag.

For research use only. We do not sell to patients.

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Description

PADI4 is a hydrolase that converts arginine residues in histones to citrulline. PADI4 promotes tumor progression by up-regulating the cytokine receptor CXCR2. PADI4 can also cause inflammation and immune responses. PADI4 Protein, Human (sf9, His) is the recombinant human-derived PADI4 protein, expressed by Sf9 insect cells , with N-His labeled tag.
Background

PADI4 is a hydrolase that converts arginine residues in histones to citrulline. PADI4 promotes tumor progression by up-regulating the cytokine receptor CXCR2. PADI4 can also cause inflammation and immune responses.
Species

Human
Source

Sf9 insect cells
Tag

N-His
Accession

Q9UM07/AAH25718.1 (M1-P663)
Gene ID
Molecular Construction
N-term
His
PADI4 (M1-P663)
Accession # Q9UM07/AAH25718.1
C-term
Synonyms
Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; PADI5; PDI5
Molecular Weight

Approximately 76.3 kDa.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

PADI4 Protein, Human (sf9, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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