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Cd84

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  • HY-P78418
    CD84/SLAMF5 Protein, Human (HEK293, His-Avi)

    Hly9-beta; Cd84; SLAMF5; LY9B; Cd84 molecule; DKFZp781E2378; Hly9-β

    		 Human HEK293
    CD84/SLAMF5 protein is a self-ligand receptor in the SLAM family that regulates the activities of various immune cells through homotypic or heterotypic cell-cell interactions. It fine-tunes its function based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD84/SLAMF5 Protein, Human (HEK293, His-Avi) is 204 a.a., with molecular weight of 40-55 kDa.
  • HY-P72463
    CD84/SLAMF5 Protein, Human (HEK293, His)

    SLAM family member 5; Cd84; Ly-9B; SLAMF5

    		 Human HEK293
    CD84/SLAMF5 protein is a self-ligand receptor in the SLAM family that regulates the activities of various immune cells through homotypic or heterotypic cell-cell interactions. It fine-tunes its function based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 Protein, Human (HEK293, His) is the recombinant human-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P72414
    CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi)

    SLAM family member 5; Cell surface antigen MAX.3; Hly9-beta; Signaling lymphocytic activation molecule 5; Cd84

    		 Human HEK293
    The CD84/SLAMF5 protein, a self-ligand receptor in the SLAM family, modulates diverse immune cell activities through homo- or heterotypic cell-cell interactions. It finely tunes its functions based on the presence or absence of small cytoplasmic adapter proteins, including SH2D1A/SAP and/or SH2D1B/EAT-2. CD84/SLAMF5 mediates NK cell cytotoxicity dependent on SH2D1A and SH2D1B, enhances T-cell proliferative responses, and amplifies IFNG secretion. It is crucial for prolonged T-cell:B-cell contact, germinal center formation, and maintaining B-cell tolerance. In mast cells, it negatively regulates immunoglobulin epsilon receptor signaling, and in macrophages, it positively regulates LPS-induced MAPK phosphorylation and NF-kappaB activation. Additionally, CD84/SLAMF5 positively regulates macroautophagy in dendritic cells and forms homodimers, interacting with CD48 molecules and various signaling proteins, including SH2D1A/SAP, SH2D1B/EAT-2, PTPN6/SHP-1, PTPN11/SHP-2, and INPP5D/SHIP1. CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD84/SLAMF5 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD84/SLAMF5 Protein, Human (Biotinylated, HEK293, His-Avi) is 199 a.a., with molecular weight of 40-50 kDa.

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