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Isoforms Recommended: ErbB3/HER3
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Erbb3

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  • HY-P74891
    HER3 Protein, Rat (HEK293, His)

    Receptor tyrosine-protein kinase Erbb-3; Erbb3; HER3

    		 Rat HEK293
    HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Rat (HEK293, His) is the recombinant rat-derived HER3 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P74892
    HER3 Protein, Rat (HEK293, Fc)

    Receptor tyrosine-protein kinase Erbb-3; Erbb3; HER3

    		 Rat HEK293
    HER3 is a tyrosine-protein kinase that is a key cell surface receptor for neuregulin. ErbB2 and ErbB3 can form dimers and activate signaling pathways including MAPK, PI3K/Akt and PLC纬 to promote tumor development. HER3 Protein, Rat (HEK293, Fc) is the recombinant rat-derived HER3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of HER3 Protein, Rat (HEK293, Fc) is 622 a.a., with molecular weight of ~115 kDa.

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