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PCSK9

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  • HY-P73340
    PCSK9 Protein, Rat (HEK293, His)
    1 Publications Verification

    Proprotein convertase subtilisin/kexin type 9; NARC-1; PC9; PCSK9

    		 Rat HEK293
    The PCSK9 protein regulates cholesterol levels by interacting with LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2. It promotes their degradation and inhibits their recycling, leading to enhanced LDLR degradation. PCSK9 also affects APOB degradation, BACE1 intermediates, ENaC surface expression, and neuronal apoptosis via LRP8/APOER2. PCSK9 Protein, Rat (HEK293, His) is the recombinant rat-derived PCSK9 protein, expressed by HEK293 , with C-6*His labeled tag.

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