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TNF

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  • HY-P7108
    TNF-alpha/TNFSF2 Protein, Rat (P.pastoris)
    2 Publications Verification

    rRtTNF-α/TNFSF2; TNF-alpha; Cachectin; DIF; TNFA; Differentiation-inducing factor

    		 Rat P. pastoris
    Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 Protein, Rat (P.pastoris) is a recombinant protein and is produced in P. pastoris.
  • HY-P70697
    TNF-alpha/TNFSF2 Protein, Rat
    2 Publications Verification

    Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Soluble Form; TNF; TNFa; TNFsf2

    		 Rat E. coli
    Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury .
  • HY-P75918
    TNFRSF3/LTBR Protein, Rat (HEK293, His)

    Tumor Necrosis Factor Receptor Superfamily Member 3; TNF-RIII; TNFCR; TNFR3

    		 Rat HEK293
    TNFRSF3/LTBR Protein, Rat (HEK293, His) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Rat (HEK293, His) is expressed by HEK293 cells and is a transmembrane protein (M222-W245) with a His tag at the C-terminus.
  • HY-P74504
    TNFRSF1A Protein, Rat (HEK293, His)

    Tumor necrosis factor receptor superfamily member 1A; CD120a; TNF-R1; TNFRSF1A

    		 Rat HEK293
    TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNFRSF1A Protein, Rat (HEK293, His) is expressed by HEK293 and has a transmembrane region (M1-A211) with a His tag at the C-terminus.
  • HY-P75640
    CD30 Ligand/TNFSF8 Protein, Rat (HEK293, Fc)

    TNF superfamily member 8; CD153; CD30 Ligand; TNFSF8

    		 Rat HEK293
    CD30 Ligand is a B cell surface antigen and a ligand for CD30 (TNFRSF8), playing an inhibitory role in CD40-mediated immunoglobulin class switching. CD30 Ligand is also a a marker for Hodgkin lymphoma and related hematologic malignancies, involves in activation and functioning of the T cell-dependent immune system. CD30 ligand is expressed by T and B lymphocytes, macrophages, and a variety of normal haematopoietic cells and derived tumours. CD30 ligand exerts pleiotropic effects on normal and malignant lymphoid cells, including death, differentiation, or cell division. As for CD30 ligand in rat contains a transmembrane domain belonging to the tumor necrosis factor (TNF) family. CD30 Ligand/TNFSF8 Protein, Rat (HEK293, Fc) is 172 amino acids in length (Q66-D237) and is expressed in the HEK293 cells with a N-terminal hFc-tag.
  • HY-P72815
    ADAM17/TACE Protein, Rat (HEK293, His)

    Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; TNF-alpha convertase; CD156b; Tace

    		 Rat HEK293
    ADAM17/TACE Protein, a pivotal enzyme, cleaves TNF-alpha and activates various cell-surface proteins like p75 TNF-receptor. It also mediates the cleavage of Notch, activates the Notch pathway, and contributes to hemostasis by shedding GP1BA. ADAM17/TACE further facilitates the cleavage of LAG3, IL6R, and FCGR3A, showcasing its significance in diverse cellular functions. ADAM17/TACE Protein, Rat (HEK293, His) is the recombinant rat-derived ADAM17/TACE protein, expressed by HEK293 , with C-10*His labeled tag. The total length of ADAM17/TACE Protein, Rat (HEK293, His) is 546 a.a., with molecular weight of 57 & 20 kDa, respectively.
  • HY-P73025
    Ephrin-A1/EFNA1 Protein, Rat (HEK293, His)

    Ephrin-A1; LERK-1; TNF alpha-induced protein 4; EFNA1; EPLG1; TNFAIP4

    		 Rat HEK293
    The Ephrin-A1/EFNA1 protein is a cell surface GPI-binding ligand of the Eph receptor and is involved in migration, repulsion, and adhesion during development. Ephrin-A1/EFNA1 Protein, Rat (HEK293, His) is the recombinant rat-derived Ephrin-A1/EFNA1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Ephrin-A1/EFNA1 Protein, Rat (HEK293, His) is 164 a.a., with molecular weight of ~23 kDa.
  • HY-P75917
    TNFRSF3/LTBR Protein, Rat (HEK293, Fc)

    Tumor Necrosis Factor Receptor Superfamily Member 3; TNF-RIII; TNFCR; TNFR3

    		 Rat HEK293
    TNFRSF3/LTBR Protein, Rat (HEK293,  Fc) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Rat (HEK293,  Fc) is expressed by HEK293 cells with a His tag at the C-terminus.
  • HY-P74505
    TNFRSF1A Protein, Rat (HEK293, Fc)

    Tumor necrosis factor receptor superfamily member 1A; CD120a; TNF-R1; TNFRSF1A

    		 Rat HEK293
    TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNFRSF1A Protein, Rat (HEK293, Fc) is expressed by HEK293 and has a transmembrane region with a Fc tag at the C-terminus.
  • HY-P75639
    CD30 Ligand/TNFSF8 Protein, Rat (HEK293)

    TNF superfamily member 8; CD153; CD30 Ligand; TNFSF8

    		 Rat HEK293
    CD30 Ligand is a B cell surface antigen and a ligand for CD30 (TNFRSF8), playing an inhibitory role in CD40-mediated immunoglobulin class switching. CD30 Ligand is also a a marker for Hodgkin lymphoma and related hematologic malignancies, involves in activation and functioning of the T cell-dependent immune system. CD30 ligand is expressed by T and B lymphocytes, macrophages, and a variety of normal haematopoietic cells and derived tumours. CD30 ligand exerts pleiotropic effects on normal and malignant lymphoid cells, including death, differentiation, or cell division. As for CD30 ligand in rat contains a transmembrane domain belonging to the tumor necrosis factor (TNF) family. CD30L Protein, Cynomolgus (HEK293, Fc) is 172 amino acids in length (Q66-D237) and is expressed in the HEK293 cells with tag free.

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