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114-86-3

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16397
    Phenformin
    5+ Cited Publications

    Phenethylbiguanide

    		 Mitochondrial Metabolism AMPK Apoptosis Metabolic Disease Cancer
    Phenformin (1-phenethylbiguanide) is an orally active antidiabetic and anticancer agent. Phenformin has an incidence of associated lactic acidosis. Phenformin acts through acting AMPK activation and blocking mTOR pathway. Phenformin is also a substrate of P-glycoprotein (P-gp), and an OXPHOS inhibitor. Phenformin induces cancer cell apoptosis .
    Phenformin
  • HY-16397A
    Phenformin hydrochloride
    5+ Cited Publications

    Phenethylbiguanide hydrochloride

    		 AMPK Autophagy Cancer
    Phenformin hydrochloride is an anti-diabetic agent from the biguanide class, can activate AMPK activity.
    Phenformin hydrochloride

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