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2635953-17-0

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120599
    Sabizabulin
    2 Publications Verification

    VERU-111; ABI-231

    		 Microtubule/Tubulin Apoptosis HPV Cancer
    VERU-111 (ABI-231) is a potent and orally active α and β tubulin inhibitor, which displays strong antiproliferative activity, with an average IC50 of 5.2 nM against panels of melanoma and prostate cancer cell lines. VERU-111 (ABI-231) suppresses tumor growth and metastatic phenotypes of cervical cancer cells via targeting HPV E6 and E7, and has potential for the treatment of prostate cancer .
    Sabizabulin
  • HY-120599A
    ABI-231 hydrochloride

    		Others Cancer
    ABI-231 hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. ABI-231 hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of ABI-231 hydrochloride shows it has a low risk of potential side effects .
    ABI-231 hydrochloride

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