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  4. ABI-231 hydrochloride

ABI-231 hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. ABI-231 hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of ABI-231 hydrochloride shows it has a low risk of potential side effects.

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ABI-231 hydrochloride Chemical Structure

ABI-231 hydrochloride Chemical Structure

CAS No. : 2635953-17-0

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ABI-231 hydrochloride Related Antibodies

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Description

ABI-231 hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. ABI-231 hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of ABI-231 hydrochloride shows it has a low risk of potential side effects[1].

Molecular Weight

413.85

Formula

C21H20ClN3O4
CAS No.
SMILES

O=C(C1=CN=C(C2=CNC3=C2C=CC=C3)N1)C4=CC(OC)=C(C(OC)=C4)OC.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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ABI-231 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ABI-2312635953-17-0ABI231ABI 231OthersInhibitorinhibitorinhibit

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