2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Sabizabulin hydrochloride

Sabizabulin hydrochloride  (Synonyms: VERU-111 hydrochloride; ABI-231 hydrochloride)

Cat. No.: HY-120599A
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Sabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects.

For research use only. We do not sell to patients.

Sabizabulin hydrochloride Chemical Structure

Sabizabulin hydrochloride Chemical Structure

CAS No. : 2635953-17-0

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Other Forms of Sabizabulin hydrochloride:

Sabizabulin hydrochloride Related Antibodies

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Description

Sabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects[1].

Molecular Weight

413.85

Formula

C21H20ClN3O4
CAS No.
SMILES

O=C(C1=CN=C(C2=CNC3=C2C=CC=C3)N1)C4=CC(OC)=C(C(OC)=C4)OC.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Sabizabulin hydrochloride Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sabizabulin2635953-17-0VERU-111ABI-231VERU111VERU 111ABI231ABI 231Endogenous MetaboliteInhibitorinhibitorinhibit

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