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Results for "

ALPK1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-156519

    NF-κB Inflammation/Immunology
    ALPK1-IN-3 is an inhibitor of ALPK1 extracted from patent WO2022063153A1 compound T007. ALPK1-IN-3 inhibits kidney proinflammatory gene expression and improves the survival rate of the animals in sepsis induced acute kidney injury animal model [1]. ALPK1-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    ALPK1-IN-3
  • HY-147561

    NF-κB Infection Inflammation/Immunology
    ALPK1-IN-1 (Compound A001) is a potent inhibitor of alpha-kinase 1 (ALPK1). ALPK1 is an intracytoplasmic serine threonine protein kinase that plays an important role in activating the innate immune response to bacteria via TRAF-interacting protein with forkhead-associated domain (TIFA) dependent proinflammatory NF-κB signaling [1].
    ALPK1-IN-1
  • HY-147562

    NF-κB Inflammation/Immunology Cancer
    ALPK1-IN-2 (compound T001) is a potent ALPK1 (alpha-kinase 1) inhibitor, with an IC50 of 95 nM. ALPK1-IN-2 also inhibits NF-κB, with an IC50 of 1.31 μM [1].
    ALPK1-IN-2
  • HY-RS00629

    Small Interfering RNA (siRNA) Others

    ALPK1 Human Pre-designed siRNA Set A contains three designed siRNAs for ALPK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ALPK1 Human Pre-designed siRNA Set A
    ALPK1 Human Pre-designed siRNA Set A

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