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ASK1-IN-6

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-160939
    ASK1-IN-6

    		MAP3K Neurological Disease Inflammation/Immunology
    ASK1-IN-6 (Compound 32) is a selective inhibitor for apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 25 nM. ASK1-IN-6 is blood brain barrier penetrate(rat Cl/Clu is 1.6/56 L/h/kg and Kp,uu is 0.46). ASK1-IN-6 exhibits anti-inflammatory avtivity and ameliorates the Alzheimer’s Disease in Tg4510 mouse model .
    ASK1-IN-6

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