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ATM Inhibitor-11

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169310
    ATM Inhibitor-11

    		ATM/ATR Cancer
    ATM Inhibitor-11 (Compound 1) is an inhibitor for ATM with an IC500 of 0.32 nM. ATM Inhibitor-11 inhibits the KAP1 phosphorylation with an IC500 of 0.97 nM. ATM Inhibitor-11 exhibits high exposure in the brain, heart and plasma of ICR mouse. ATM Inhibitor-11 exhibits anti-tumor efficacy in NCI-H441 xenograft mouse model .
    ATM Inhibitor-11

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