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Aspergillus oryzae

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amylases (1) Apoptosis (1) Biochemical Assay Reagents (2) CDK (2) DNA/RNA Synthesis (2) Endogenous Metabolite (4) Fungal (2) Isotope-Labeled Compounds (2) NF-κB (2) Parasite (3) Tyrosinase (2)
By Research Areas:	Cancer (4) Infection (5) Inflammation/Immunology (2) Metabolic Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2228

Proteinase, Aspergillus oryzae	Biochemical Assay Reagents	Cancer
Proteinase, Aspergillus oryzae refers to the enzymes with proteolytic activity.

HY-P0229

Ribonulease T1, Aspergillus oryzae Rnase T1	DNA/RNA Synthesis	Others
Ribonulease T1, Aspergillus oryzae (Rnase T1), is commonly used in biochemical research. Ribonuclease T1 is an endonuclease that can specifically degrade single stranded RNA. Ribonuclease T1 can form nucleoside 2 ', 3 '-cyclic phosphoric acid intermediates to cut the phosphodiester bond between 3' -guanosine residues and adjacent nucleoside 5 '-OH groups to produce 3' -GMP terminal oligonucleotides .

HY-101399

γ-Glu-Phe γ-Glutamylphenylalanine	Endogenous Metabolite	Others
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-101399A

γ-Glu-Phe TFA γ-Glutamylphenylalanine TFA	Endogenous Metabolite	Others
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-B2192A

Diastase, Aspergillus oryzae Maltin	Biochemical Assay Reagents	Others
Diastase is an amylase from Aspergillus oryzae that hydrolyzes starch into sugars .

HY-P2762

α-Amylase from Aspergillus oryzae	Amylases	Others
α-Amylase from Aspergillus oryzae is an amylase. α-Amylase from Aspergillus oryzae can be used for various biochemical studies .

HY-P2773

Nuclease S1, Aspergillus oryzae	DNA/RNA Synthesis	Others
Nuclease S1, Aspergillus oryzae is a specific endonuclease that degrades single stranded DNA (ssDNA) and RNA. Nuclease S1 can also remove protruding single-strand ends from double-stranded DNA .

HY-E70350

Ribonuclease T2, Aspergillus oryzae	Endogenous Metabolite	Others
Ribonuclease T2, Aspergillus oryzae is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-126795

Aspergillin PZ	Fungal	Infection
Aspergillin PZ is a novel isoindole-alkaloid from Aspergillus awamori. Aspergillin PZ induces conidia of P. oryzae to deform moderately .

HY-N8512

Asperfuran	Fungal	Infection
Asperfuran is an antifungal dihydrobenzofuran derivative produced by a strain of Aspergillus oryzae. Asperfuran weakly inhibits chitin synthase from Coprinus cinereus. Asperfuran shows weak cytotoxicity In HeLa S3 and L1210 cells with an IC₅₀ of 25 μg/ml .

HY-W357146

2-Phenylethyl β-D-galactopyranoside Phenethyl β-D-galactoside	Others	Others
2-Phenylethyl β-D-galactopyranoside (Phenethyl β-D-galactoside) can be synthesized catalyzed by Aspergillus oryzae β-galactosidase .

HY-W010476S1

2,3,5-Trimethylpyrazine-d3	Endogenous Metabolite Isotope-Labeled Compounds	Metabolic Disease
2,3,5-Trimethylpyrazine-d₃ is deuterated labeled Kojic acid (HY-W050154). Kojic acid is a natural substance produced by Aspergillus oryzae, also used as an anti-oxidant and radio-protective agent .

HY-N12534

Monaspin B	Apoptosis	Cancer
Monaspin B is a natural product produced by the co-culture of Monascus purpureus and Aspergillus oryzae. Monaspin B exerts anti-proliferation activity by inducing apoptosis of HL-60 cells, IC₅₀ 160 nM. Monaspin B has antitumor activity .

HY-N8285

Sporogen AO-1	Parasite	Infection
Sporogen AO-1 is a fungal metabolite originally isolated from the fungusAspergillus oryzae. Sporogen AO-1 has significant antimalarial activity againstplasmodium falciparum, with an IC₅₀ value of 1.53 μM, and also has certain cytotoxicity .

HY-101399S

γ-Glu-(Phe-13C9,15N) γ-Glutamylphenylalanine-¹³C₉,¹⁵N	Isotope-Labeled Compounds	Others
γ-Glu-(Phe- ¹³C9, ¹⁵N) is the ¹³C and ¹⁵N labeled isotope of γ-Glu-Phe(HY-101399).γ-Glu-Phe or the postenzymatic reaction mixture enhanced the umami intensity of commercial soy sauce and model chicken soup.

HY-W050154

Kojic acid	Parasite Tyrosinase NF-κB CDK	Infection Inflammation/Immunology Cancer
Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC₅₀ of 182.7 μM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-κB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity .

HY-W050154R

Kojic acid (Standard)	Parasite Tyrosinase NF-κB CDK	Infection Inflammation/Immunology Cancer
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .

Proteinase, Aspergillus oryzae	Biochemical Assay Reagents
Proteinase, Aspergillus oryzae refers to the enzymes with proteolytic activity.

Cat. No.	Product Name	Target	Research Area

HY-101399

γ-Glu-Phe γ-Glutamylphenylalanine	Endogenous Metabolite	Others
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-101399A

γ-Glu-Phe TFA γ-Glutamylphenylalanine TFA	Endogenous Metabolite	Others
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101399

γ-Glu-Phe γ-Glutamylphenylalanine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-101399A

γ-Glu-Phe TFA γ-Glutamylphenylalanine TFA	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-W050154

Kojic acid	Infection Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Parasite Tyrosinase NF-κB CDK
Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC₅₀ of 182.7 μM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-κB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity .

HY-126795

Aspergillin PZ	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Fungal
Aspergillin PZ is a novel isoindole-alkaloid from Aspergillus awamori. Aspergillin PZ induces conidia of P. oryzae to deform moderately .

HY-N8512

Asperfuran	Infection Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields	Fungal
Asperfuran is an antifungal dihydrobenzofuran derivative produced by a strain of Aspergillus oryzae. Asperfuran weakly inhibits chitin synthase from Coprinus cinereus. Asperfuran shows weak cytotoxicity In HeLa S3 and L1210 cells with an IC₅₀ of 25 μg/ml .

HY-N12534

Monaspin B	Structural Classification Natural Products Microorganisms Source classification	Apoptosis
Monaspin B is a natural product produced by the co-culture of Monascus purpureus and Aspergillus oryzae. Monaspin B exerts anti-proliferation activity by inducing apoptosis of HL-60 cells, IC₅₀ 160 nM. Monaspin B has antitumor activity .

HY-N8285

Sporogen AO-1	Structural Classification Natural Products Microorganisms Source classification	Parasite
Sporogen AO-1 is a fungal metabolite originally isolated from the fungusAspergillus oryzae. Sporogen AO-1 has significant antimalarial activity againstplasmodium falciparum, with an IC₅₀ value of 1.53 μM, and also has certain cytotoxicity .

HY-W050154R

Kojic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Parasite Tyrosinase NF-κB CDK
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .

Cat. No.	Product Name	Chemical Structure

HY-W010476S1

2,3,5-Trimethylpyrazine-d3
2,3,5-Trimethylpyrazine-d₃ is deuterated labeled Kojic acid (HY-W050154). Kojic acid is a natural substance produced by Aspergillus oryzae, also used as an anti-oxidant and radio-protective agent .

HY-101399S

γ-Glu-(Phe-13C9,15N)
γ-Glu-(Phe- ¹³C9, ¹⁵N) is the ¹³C and ¹⁵N labeled isotope of γ-Glu-Phe(HY-101399).γ-Glu-Phe or the postenzymatic reaction mixture enhanced the umami intensity of commercial soy sauce and model chicken soup.

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Aspergillus oryzae

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products