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Results for "

Chemiluminescence

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

10

Fluorescent Dye

1

Biochemical Assay Reagents

2

MCE Kits

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W127716
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
    1 Publications Verification

    		 Fluorescent Dye Cancer
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
  • HY-15922A
    Luminol sodium salt
    1 Publications Verification

    		 Fluorescent Dye Others
    Luminol sodium salt is a chemical that exhibits chemiluminescence with pKa values of 6.74 and 15.1. Luminol sodium salt exhibits chemiluminescence (CL) at 425 nm λmax. Luminol sodium salt is commonly used in forensics as a diagnostic tool for the detection of blood stains .
    Luminol sodium salt
  • HY-15922
    Luminol
    1 Publications Verification

    Diogenes reagent

    		 Fluorescent Dye Others
    Luminol is a chemical that exhibits chemiluminescence with pKa values of 6.74 and 15.1. Luminol exhibits chemiluminescence (CL) at 425 nm λmax. Luminol is commonly used in forensics as a diagnostic tool for the detection of blood stains .
    Luminol
  • HY-W000357
    4-(Imidazol-1-yl)phenol

    		Biochemical Assay Reagents Others
    4-(Imidazol-1-yl)phenol is a highly potent signal enhancer in a horseradish peroxidase (HRP)-luminol chemiluminescence (CL) immunoassay .
    4-(Imidazol-1-yl)phenol
  • HY-D0892
    NSP-DMAE-NHS

    		Biochemical Assay Reagents Others
    NSP-DMAE-NHS is an acridinium ester chemiluminescence reagent containing N-sulfopropyl group. It is useful in the clinical diagnostics industry, especially in automated immunochemistry analyzers such as the ADVIA Centaur system from Siemens Healthcare Diagnostics.
    NSP-DMAE-NHS
  • HY-D0720
    Lucigenin
    4 Publications Verification

    NSC-151912; L-6868

    		 Fluorescent Dye Reactive Oxygen Species Others
    Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O 2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .
    Lucigenin
  • HY-12591
    D-Luciferin sodium
    Maximum Cited Publications
    39 Publications Verification

    D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium

    		 Fluorescent Dye Others
    D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
    D-Luciferin sodium
  • HY-W099490
    Bis[3,4,6-trichloro-2-(pentyloxycarbonyl)phenyl] oxalate

    		Fluorescent Dye Others
    Bis[3,4,6-trichloro-2-(pentyloxycarbonyl)phenyl] oxalate is a fluorescent dye that can be used for generation of chemiluminescence .
    Bis[3,4,6-trichloro-2-(pentyloxycarbonyl)phenyl] oxalate
  • HY-118315
    L-012

    		Others Reactive Oxygen Species Others
    L-012 is a chemiluminescent probe that reacts with various types of ROS produced by activated neutrophils in human blood, oral cavity, and rat peritoneum and produces strong chemiluminescence (CHL). L-012 produces CHL primarily by reacting with hydroxyl radicals and hypochlorite. L-012 can be used to study ROS generation in complex biological systems and the role of ROS in the pathogenesis of various diseases .
    L-012
  • HY-W415108
    10-Methyl-9-(phenoxycarbonyl) acridinium trifluoromethanesulfonate

    		Fluorescent Dye Others
    10-Methyl-9-(phenoxycarbonyl) acridinium trifluoromethanesulfonate is an acridinium ester that produces fluorescent 10-methyl-9-acridone upon oxidation with hydrogen peroxide, persulfate, and other oxidants under alkaline conditions. 10-Methyl-9-(phenoxycarbonyl) acridinium trifluoromethanesulfonate can be used in chemiluminescent assays, enzyme, antigen, antibody, and hormone immunoassays, and for the detection of oxidants in environmental, biological, and pharmaceutical samples .
    10-Methyl-9-(phenoxycarbonyl) acridinium trifluoromethanesulfonate
  • HY-12591A
    D-Luciferin
    Maximum Cited Publications
    39 Publications Verification

    D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin

    		 Fluorescent Dye Others
    D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
    D-Luciferin
  • HY-12591B
    D-Luciferin potassium
    Maximum Cited Publications
    39 Publications Verification

    D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium

    		 Fluorescent Dye Others
    D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
    D-Luciferin potassium
  • HY-W008820R
    Glutaric acid (Standard)

    		Endogenous Metabolite Metabolic Disease
    Glutaric acid (Standard) is the analytical standard of Glutaric acid. This product is intended for research and analytical applications. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I . In Vitro: Glutaric acid (GA) at concentrations of 1 and 2 mM is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM .
    Glutaric acid (Standard)
  • HY-100315
    XL 999

    Tyrosine kinase-IN-1

    		 VEGFR PDGFR FGFR Cardiovascular Disease
    Kinase Assay: Kinase Inhibition Assays Kinase activities of KDR and PDGFRα are measured as the percent of ATP consumed following the kinase reaction using luciferaseluciferin-coupled chemiluminescence. Kinase reactions are initiated by combining test compound (XL 999), ATP, kinases and substrates in a 20 mL volume using 384-well microtiter plates. For KDR, the final reaction mixture contained 3 mM ATP, 1.6 mM poly(Glu, Tyr) 4:1 and 1.5 nM KDR of residues D807-V1356 with an N-terminal GST tag. For PDGFRα, the final reaction mixture contained 2 mM ATP, 10 mM MBP and 14 nM PDGFRα of residues Q551-L1089 with an N-terminal GST tag. The reaction mixture is incubated at room temperature for 4 h (KDR) or 2 h PDGFRα before a 20 mL aliquot of Kinase Glo is added and luminescence signal is measured using a Victor2 plate reader. Total ATP consumption is limited below 50% .
    XL 999

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