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Results for "

DEVDase

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Fluorescent Dye

5

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P0109A
    Z-FA-FMK
    3 Publications Verification

    (1S)-Z-FA-FMK

    		 SARS-CoV Cathepsin Apoptosis Caspase Infection Cancer
    Z-FA-FMK ((1S)-Z-FA-FMK) is a potent Cathepsin B and L inhibitor. Z-FA-FMK blocks the induction of DEVDase activity, DNA fragmentation, and externalization of phosphatidylserine by selective synthetic retinoid-related molecules (RRMs). Z-FA-FMK inhibits apoptosis. Z-FA-FMK inhibits caspase activity and selectively inhibits recombinant effector caspases 2, -3, -6, and -7. Z-FA-FMK is a viral inhibitor. Z-FA-FMK inhibits reovirus replication in a susceptible host .
    Z-FA-FMK
  • HY-P1001
    Ac-DEVD-CHO
    Maximum Cited Publications
    31 Publications Verification

    		 Caspase Cancer
    Ac-DEVD-CHO is a specific Caspase-3 inhibitor with a Ki value of 230 pM.
    Ac-DEVD-CHO
  • HY-P1006
    Ac-DEVD-pNA
    1 Publications Verification

    		 Caspase Others
    Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.
    Ac-DEVD-pNA
  • HY-P1003
    Ac-DEVD-AMC
    4 Publications Verification

    		 Fluorescent Dye Others
    Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
    Ac-DEVD-AMC
  • HY-P1005
    Ac-DEVD-AFC
    5+ Cited Publications

    		 Fluorescent Dye Cancer
    Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm).
    Ac-DEVD-AFC
  • HY-P5830
    Biotin-DEVD-CHO

    		Caspase Others
    Biotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage .
    Biotin-DEVD-CHO

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