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Pathways Recommended: Antibody-drug Conjugate/ADC Related
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Exatecan-d<sub>5</sub> derivative for ADC

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13631DS
    Dxd-d5

    Exatecan-d<sub>5sub> derivative for ADC

    		 Topoisomerase ADC Cytotoxin Cancer
    Dxd-d5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) [1].
    Dxd-d5

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