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Results for "

Flavonolignan

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

13

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0779A
    Silybin
    2 Publications Verification

    Silibinin

    		 Apoptosis Inflammation/Immunology Cancer
    Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .
    Silybin
  • HY-N0647
    Silychristin
    1 Publications Verification

    		 Monocarboxylate Transporter Endocrinology
    Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .
    Silychristin
  • HY-N7045
    Isosilybin B
    1 Publications Verification

    		 Androgen Receptor Apoptosis Cancer
    Isosilybin B, a flavonolignan isolated from Silybum marianum, has anti-prostate cancer (PCA) activity via inhibiting proliferation and inducing G1 phase arrest and apoptosis. Isosilybin B causes androgen receptor (AR) degradation .
    Isosilybin B
  • HY-N7046
    Silybin B

    Silibinin B

    		 Amyloid-β Neurological Disease Cancer
    Silybin B (Silibinin B), a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease agent candidate .
    Silybin B
  • HY-N10986
    (±)-Hydnocarpin

    		Bacterial Infection Inflammation/Immunology
    (±)-Hydnocarpin is a flavonolignan. (±)-Hydnocarpin can inhibit the growth of S. aureus with a MIC50 value of 3.1 μM .
    (±)-Hydnocarpin
  • HY-129584
    Lepidiline B

    		Others Inflammation/Immunology
    Lepidiline B is a flavonolignan isolated from the roots of Brassicaceae Lepidium meyenii. Lepidiline B exhibits anti-inflammation activities in human cancer cell lines .
    Lepidiline B
  • HY-N12360A
    2,3-Dehydrosilybin B

    		Others Others
    2,3-Dehydrosilybin B is an enantiomer formed by the oxidation of the natural flavonolignans silybin A .
    2,3-Dehydrosilybin B
  • HY-N8180
    Silyamandin

    		Others Others
    Silyamandin is a flavonolignan compound. Silydianin can form Silyamandin through oxidative degradation .
    Silyamandin
  • HY-N0779AR
    Silybin (Standard)

    		Apoptosis Inflammation/Immunology Cancer
    Silybin (Standard) is the analytical standard of Silybin. This product is intended for research and analytical applications. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .
    Silybin (Standard)
  • HY-N0647R
    Silychristin (Standard)

    		Monocarboxylate Transporter Endocrinology
    Silychristin (Standard) is the analytical standard of Silychristin. This product is intended for research and analytical applications. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .
    Silychristin (Standard)
  • HY-N7043
    Isosilybin A
    1 Publications Verification

    		 Apoptosis Cancer
    Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis .
    Isosilybin A
  • HY-N7046R
    Silybin B (Standard)

    		Amyloid-β Neurological Disease Cancer
    Silybin B (Standard) is the analytical standard of Silybin B. This product is intended for research and analytical applications. Silybin B (Silibinin B), a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease agent candidate .
    Silybin B (Standard)
  • HY-N7043R
    Isosilybin A (Standard)

    		Apoptosis Cancer
    Isosilybin A (Standard) is the analytical standard of Isosilybin A. This product is intended for research and analytical applications. Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis .
    Isosilybin A (Standard)

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