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GX

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By Targets:	Autophagy (2) Bcl-2 Family (2) Calcium Channel (1) Drug Metabolite (1) Endogenous Metabolite (1) ERK (1) Fluorescent Dye (1) MEK (1) NF-κB (1) Parasite (2) Sodium Channel (4)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (2) Neurological Disease (3)

10

Inhibitors & Agonists

1

Fluorescent Dye

1

Biochemical Assay Reagents

4

Recombinant Proteins

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

GX-201	Sodium Channel	Inflammation/Immunology
GX-201 is a selective Na_V1.7 inhibitor, with an IC₅₀ of <3.2 nM for hNa_V1.7 .

Obatoclax Mesylate Maximum Cited Publications 10 Publications Verification GX15-070 Mesylate	Bcl-2 Family Autophagy Parasite	Infection Cancer
Obatoclax Mesylate (GX15-070 Mesylate), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a K_i of 220 nM for BCL-2 . Obatoclax Mesylate induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax Mesylate has anti-cancer and broad-spectrum antiparasitic activity .

Alcian Blue 8GX 4 Publications Verification	Fluorescent Dye	Others
Alcian Blue 8GX is a commonly used phthalocyanine dye that binds to glycoproteins and glycosaminoglycans. Alcian Blue 8GX has a wide range of applications in biological staining, including proteins in brain tumors and DNA in cells and tissues .

Glycinexylidide GX	Sodium Channel ERK MEK NF-κB Drug Metabolite	Cancer
Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local agent that can suppress or relieve pain, that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease .

GX-585	Others	Neurological Disease Inflammation/Immunology
GX-585 is a sulfonamide analog that acts as a Nav1.7 channel inhibitor, demonstrating analgesic activity in treating neuropathic pain and inflammation.

GX-674	Sodium Channel	Cardiovascular Disease Neurological Disease
GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC₅₀ of 0.1 nM at -40 mV .

GX-936 PF-05196233	Sodium Channel	Neurological Disease
GX-936 (PF-05196233), a potent and Nav1.7-subtype selective inhibitor, binds to the activated state of voltage-sensor domain IV (VSD4) .

Obatoclax GX15-070	Bcl-2 Family Autophagy Parasite	Infection Cancer
Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a K_i of 220 nM for BCL-2 . Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum antiparasitic activity .

Teludipine hydrochloride GR53992B; GX1296B	Calcium Channel	Cancer
Teludipine is a lipophilic calcium channel blocker.

AMK-GX Immobilized Penicillin G acylase	Endogenous Metabolite	Others
AMK-GX (Immobilized Penicillin G acylase) is an immobilized penicillin acylase with improved temperature and pH stability. AMK-GX has reusable performance and high recovery rates, retaining much of its original activity after 12 cycles. Among them, AMK-GX can catalyze penicillin G (PG) to generate 6-aminopenicillanic acid (6-APA) and 7-aminodeacetoxycephalosporanic acid, which are key intermediates for β-lactam antibiotics .

Cat. No.	Product Name	Type

Alcian Blue 8GX 4 Publications Verification	Dyes
Alcian Blue 8GX is a commonly used phthalocyanine dye that binds to glycoproteins and glycosaminoglycans. Alcian Blue 8GX has a wide range of applications in biological staining, including proteins in brain tumors and DNA in cells and tissues .

Cat. No.	Product Name	Type

Glycinexylidide GX	Biochemical Assay Reagents
Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local agent that can suppress or relieve pain, that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease .

Species:	Human (4)
Tag:	His (3) SUMO (1) Fc (1)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

	RAC2 Protein, Human (His) Ras-related C3 botulinum toxin substrate 2; GX; Small G protein; p21-Rac2	Human	E. coli
	The RAC2 protein is a plasma membrane-associated small GTPase that dynamically regulates cellular responses by cycling between an active GTP-bound state and an inactive GDP-bound state. In its active state, RAC2 regulates secretory function, phagocytosis, and epithelial cell polarization. RAC2 Protein, Human (His) is the recombinant human-derived RAC2 protein, expressed by E. coli , with N-His labeled tag. The total length of RAC2 Protein, Human (His) is 189 a.a., with molecular weight of ~25 kDa.

	GNAZ Protein, Human (His-SUMO) GX; alpha chain; GNAZ; GNAZ_HUMAN; Guanine nucleotide-binding protein Gz; subunit alpha; Gz-alpha	Human	E. coli
	GNAZ proteins are members of G proteins that are crucial in regulating or transducing signals in a variety of transmembrane signaling systems. G proteins have three units, α, β, and γ, and play a key role in signal transmission across cell membranes. GNAZ Protein, Human (His-SUMO) is the recombinant human-derived GNAZ protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of GNAZ Protein, Human (His-SUMO) is 354 a.a., with molecular weight of ~56.8 kDa.

	B3GALT5 Protein, Human (HEK293, Fc) Beta-1,3-galactosyltransferase 5; Beta3Gal-T5; Beta-3-GX-T5	Human	HEK293
	B3GALT5 protein plays a pivotal role in catalyzing the transfer of galactose (Gal) to GlcNAc-based acceptors, exhibiting a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Additionally, it demonstrates efficient acceptor activity with glycolipid LC3Cer. B3GALT5 Protein, Human (HEK293, Fc) is the recombinant human-derived B3GALT5 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of B3GALT5 Protein, Human (HEK293, Fc) is 282 a.a., with molecular weight of ~62 kDa.

	B3GALT5 Protein, Human (sf9, His) Beta-1,3-galactosyltransferase 5; Beta3Gal-T5; Beta-3-GX-T5	Human	Sf9 insect cells
	B3GALT5 protein plays a pivotal role in catalyzing the transfer of galactose (Gal) to GlcNAc-based acceptors, exhibiting a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Additionally, it demonstrates efficient acceptor activity with glycolipid LC3Cer. B3GALT5 Protein, Human (sf9, His) is the recombinant human-derived B3GALT5 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of B3GALT5 Protein, Human (sf9, His) is 282 a.a., with molecular weight of ~35.2 KDa.

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	Rac Antibody (YA3290) Cell migration-inducing gene 5 protein; EN-7; GX; p21-Rac1; p21-Rac2; p21-Rac3; RAC1; RAC2; RAC3; TC25	WB	Human, Mouse, Rat
	Rac Antibody (YA3290) is a biotin-conjugated non-conjugated IgG antibody, targeting Rac, with a predicted molecular weight of 21 kDa. Rac Antibody (YA3290) can be used for WB experiment in human, mouse, rat background.

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