B3GALT5 Protein, Human (sf9, His)

B3GALT5 protein plays a pivotal role in catalyzing the transfer of galactose (Gal) to GlcNAc-based acceptors, exhibiting a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Additionally, it demonstrates efficient acceptor activity with glycolipid LC3Cer. B3GALT5 Protein, Human (sf9, His) is the recombinant human-derived B3GALT5 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of B3GALT5 Protein, Human (sf9, His) is 282 a.a., with molecular weight of ~35.2 KDa.

Beta-1,3-Galactosyltransferase 5 (B3GALT5) is an enzyme that plays a key role in glycosylation by catalyzing the transfer of a galactose (Gal) residue to GlcNAc-based acceptors. This enzyme exhibits a preference for the core3 O-linked glycan structure, specifically GlcNAc(beta1,3)GalNAc. Additionally, B3GALT5 demonstrates efficiency in using glycolipid LC3Cer as an acceptor substrate. The transfer of galactose by B3GALT5 is integral to the biosynthesis of complex glycan structures, contributing to the diversity of glycoconjugates involved in cellular recognition, signaling, and adhesion processes. Understanding the substrate specificity of B3GALT5 provides insights into its role in glycosylation pathways and the modulation of cellular functions through the generation of specific glycan structures.

Human

Sf9 insect cells

N-His

Q9Y2C3 (N29-V310)

10317  [NCBI]

Approximately 35.2 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.