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JQ-1 (carboxylic acid)-NH-C2-NH-COOH

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Drug Metabolite (2) E3 Ligase Ligand-Linker Conjugates (2) Fluorescent Dye (2) Liposome (5) PROTAC Linkers (2)
By Research Areas:	Cancer (7) Infection (2) Metabolic Disease (1)
Oligonucleotides:	Pegylated Lipids (1) Phospholipids (4)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Oligonucleotides

Targets Recommended: Amino Acid Derivatives Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1040

CY5.5-COOH Cyanine 5.5 carboxylic acid	Fluorescent Dye	Others
CY5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye, is commonly used in bioimaging. CY5.5-COOH shows narrow absorption spectrum, and high sensitivity and stability .

HY-145991

Ribavirin carboxylic acid	Drug Metabolite	Infection
Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity .

HY-D1040A

CY5.5-COOH chloride Cyanine 5.5 carboxylic acid chloride	Fluorescent Dye	Others
CY5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye, is commonly used in bioimaging. CY5.5-COOH chloride shows narrow absorption spectrum, and high sensitivity and stability .

HY-169082

JQ-1 (carboxylic acid)-NH-C2-NH-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
JQ-1 (carboxylic acid)-NH-C2-NH-COOH is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates), which is composed of JQ-1 carboxylic acid (HY-78695) and the corresponding linker: (2-Aminoethyl)carbamic acid (HY-W398806). JQ-1 (carboxylic acid)-NH-C2-NH-COOH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules .

HY-145991R

Ribavirin carboxylic acid (Standard)	Drug Metabolite	Infection
Ribavirin carboxylic acid (Standard) is the analytical standard of Ribavirin carboxylic acid. This product is intended for research and analytical applications. Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity .

HY-141651

(S,R,S)-AHPC-C3-COOH	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C3-COOH (compound 28i) is a carboxylic acid derivative of the VHL E3 ubiquitin ligase ligand-Linker conjugate. (S,R,S)-AHPC-C3-COOH can be used to synthesize PROTACs .

HY-W591461

DSPE-PEG-COOH, MW 2000	Liposome	Cancer
DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.

HY-140015A

(S,E)-TCO2-PEG3-acid	PROTAC Linkers	Cancer
(S)-TCO-PEG3-acid is a click chemistry PEG linker with a terminal carboxylic acid(COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S)-TCO-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-115435

1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium DMPS-Na; Dimyristoyl phosphatidylserine sodium	Liposome	Cancer
1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with myristic acid tails (14:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of liposome.

HY-141161A

(S,E)-TCO2-PEG8-acid	PROTAC Linkers	Cancer
(S)-TCO-PEG8-acid is a click chemistry PEG linker with a terminal carboxylic acid(COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S)-TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. (S)-TCO-PEG8-acid is longer than (S)-TCO-PEG3-acid .

HY-W440985

DLPS 1,2-dilauroyl-sn-glycero-3-phospho-L-serine	Liposome	Cancer
DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.

HY-W440986

Distearoylphosphatidylserine sodium DSPS sodium	Liposome	Others
Distearoylphosphatidylserine sodium is an anionic phospholipid with stearic acid tails (18:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.

HY-W714524

1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium 1,2-POPS; 1,2-POPS; 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium; 1-Hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine sodium salt	Liposome	Metabolic Disease
2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes.

HY-W440955

Stearic acid-PEG-CH2CO2H (MW 3400)	Biochemical Assay Reagents	Others
Stearic acid-PEG-CH2CO2H, MW 3400 is a lipophilic thiol-reactive PEG polymer. The stearic acid can be used to encapsulate hydrophobic therapeutic agents while the PEG chain increases overall water solubility and biocompatibilty. Reaction between carboxylic acid (-COOH) and amine (-NH2) vai condensation in the presence of activator, such as HATU or EDC, generates a stable amide linkage. Reagent grade, for research use only.

Cat. No.	Product Name	Type

HY-D1040

CY5.5-COOH Cyanine 5.5 carboxylic acid	Fluorescent Dyes/Probes
CY5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye, is commonly used in bioimaging. CY5.5-COOH shows narrow absorption spectrum, and high sensitivity and stability .

HY-D1040A

CY5.5-COOH chloride Cyanine 5.5 carboxylic acid chloride	Fluorescent Dyes/Probes
CY5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye, is commonly used in bioimaging. CY5.5-COOH chloride shows narrow absorption spectrum, and high sensitivity and stability .

Cat. No.	Product Name	Type

HY-W440955

Stearic acid-PEG-CH2CO2H (MW 3400)	Drug Delivery
Stearic acid-PEG-CH2CO2H, MW 3400 is a lipophilic thiol-reactive PEG polymer. The stearic acid can be used to encapsulate hydrophobic therapeutic agents while the PEG chain increases overall water solubility and biocompatibilty. Reaction between carboxylic acid (-COOH) and amine (-NH2) vai condensation in the presence of activator, such as HATU or EDC, generates a stable amide linkage. Reagent grade, for research use only.

Stearic acid-PEG-CH2CO2H (MW 3400)

Drug Delivery

Stearic acid-PEG-CH2CO2H, MW 3400 is a lipophilic thiol-reactive PEG polymer. The stearic acid can be used to encapsulate hydrophobic therapeutic agents while the PEG chain increases overall water solubility and biocompatibilty. Reaction between carboxylic acid (-COOH) and amine (-NH2) vai condensation in the presence of activator, such as HATU or EDC, generates a stable amide linkage. Reagent grade, for research use only.

Cat. No.	Product Name		Classification