DSPE-PEG-COOH, MW 2000

Cat. No.: HY-W591461 Purity: 99.95%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.

For research use only. We do not sell to patients.

DSPE-PEG-COOH, MW 2000 Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.

Molecular Weight

2000.00

Formula

C₅₀H₉₄N₂NaO₁₄P

Appearance

Solid

Color

White to off-white

SMILES

[H][C@@](COC(CCCCCCCCCCCCCCCCC)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(OCCOCCNC(CCC(O)=O)=O)=O)(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (50.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5000 mL	2.5000 mL	5.0000 mL
5 mM	0.1000 mL	0.5000 mL	1.0000 mL
10 mM	0.0500 mL	0.2500 mL	0.5000 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

Select Batch:

Data Sheet (263 KB) SDS (251 KB)

COA (241 KB) HNMR (327 KB) RP-HPLC (246 KB)

Handling Instructions (2659 KB)

References

[1]. Juliano R L, et al. Liposomes as a drug delivery system for antisense oligonucleotides[J]. Antisense research and development, 1992, 2(2): 165-176. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.5000 mL	2.5000 mL	5.0000 mL	12.5000 mL
	5 mM	0.1000 mL	0.5000 mL	1.0000 mL	2.5000 mL
	10 mM	0.0500 mL	0.2500 mL	0.5000 mL	1.2500 mL
	15 mM	0.0333 mL	0.1667 mL	0.3333 mL	0.8333 mL
	20 mM	0.0250 mL	0.1250 mL	0.2500 mL	0.6250 mL
	25 mM	0.0200 mL	0.1000 mL	0.2000 mL	0.5000 mL
	30 mM	0.0167 mL	0.0833 mL	0.1667 mL	0.4167 mL
	40 mM	0.0125 mL	0.0625 mL	0.1250 mL	0.3125 mL