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MEN1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Epigenetic Reader Domain (2) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (2) Neurological Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Menin-MLL inhibitor-22	Epigenetic Reader Domain	Cancer
Menin-MLL inhibitor-22 (compound C20) is an orally active inhibitor of the interaction between menin and mixed lineage leukemia (MLL) (IC₅₀=7 nM). Menin-MLL inhibitor-22 binds menin protein and inhibits cancer cell growth (MV4 cells, IC₅₀=0.3 μM). Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome) ^[1].

MEN1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MEN1 Human Pre-designed siRNA Set A contains three designed siRNAs for MEN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MEN1 Human Pre-designed siRNA Set A MEN1 Human Pre-designed siRNA Set A

Menin-MLL inhibitor 34	Epigenetic Reader Domain	Cancer
Menin-MLL inhibitor 34 (Compound 37) is a selective and potent Menin-MLL inhibitor, with an IC₅₀ of 18.21 nM for Menin. Menin-MLL inhibitor 34 has long-lasting anti-leukemic effects by reducing Menin protein levels and down-regulating MEN1 transcription ^[1].

CGRP antagonist 4	Others	Neurological Disease
CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes .

Cat. No.	Compare	Product Name	Species	Source

	Menin Protein, Human MEN1; MENin	Human	E. coli
	The Menin protein is an important component of the MLL/SET1 HMT complex, which methylates “Lys-4” of histone H3. It acts as a transcriptional regulator, inhibiting telomerase expression and inhibiting cell proliferation through TGFB1. Menin Protein, Human is the recombinant human-derived Menin protein, expressed by E. coli , with tag free. The total length of Menin Protein, Human is 615 a.a., .

	Menin Protein, Human (His) MEN1; MENin	Human	E. coli
	The Menin protein is an important component of the MLL/SET1 HMT complex, which methylates “Lys-4” of histone H3. It acts as a transcriptional regulator, inhibiting telomerase expression and inhibiting cell proliferation through TGFB1. Menin Protein, Human (His) is the recombinant human-derived Menin protein, expressed by E. coli , with N-6*His labeled tag. The total length of Menin Protein, Human (His) is 615 a.a., .

	Beta-lactamase CTX-M-1/Bla Protein, E.coli (His) bla; MEN1Beta-lactamase CTX-M-1; EC 3.5.2.6; Beta-lactamase MEN-1; Cefotaximase 1	E.coli	E. coli
	Beta-lactamase CTX-M-1/Bla protein is a broad-spectrum beta-lactamase that greatly contributes to antibiotic resistance by hydrolyzing penicillins and cephalosporins (including third-generation drugs). Beta-lactamase CTX-M-1/Bla Protein, E.coli (His) is the recombinant E. coli-derived Beta-lactamase CTX-M-1/Bla protein, expressed by E. coli , with N-His labeled tag.

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	Menin Antibody (YA1673) MEN1; SCG2; MENin	WB, IP	Human, Rat
	Menin Antibody (YA1673) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1673), targeting Menin, with a predicted molecular weight of 68 kDa (observed band size: 68 kDa). Menin Antibody (YA1673) can be used for WB, IP experiment in human, rat background.

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MEN1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
MEN1 Human Pre-designed siRNA Set A contains three designed siRNAs for MEN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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